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There are interactions between cannabis and opioids, and Tramadol is a synthetic opioid. The clinical significance of these interactions is dose-dependent, and  There are possible interactions that could make you drowsy or dizzy. You should only use this combination with an okay from your doctor and  A Major Drug Interaction exists between cannabis and tramadol. View detailed information regarding this drug interaction. 29 Nov 2018 Why are doctors so attached to their opioids when there are safer, effective options available? Know your options, says Bottom Line CEO Sarah 

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